With that said, here are 12 things you should know about both sides ahead of kick-off (stats supplied by OPTA):
1. Arsenal have lost just one of 19 previous home Premier League matches against Manchester City (W12 D6 L1).
2. Manchester City are looking to the double over Arsenal in a league season for the first time since 1975-76.
3. The last seven Premier League meetings between these two sides have produced 27 goals – 3.86 per game, on average.
5. This is only the second time that Arsenal have found themselves outside the top five in the Premier League as late as April in a season under Wenger – the other occasion was in April 2006.
6. On the day of this game, Arsenal will have spent 1209 days behind Manchester City in the Premier League table since the start of 2011-12. In the six Premier League seasons prior to this (2005-06 to 2010-11) they spent just 246 days behind Man City in the Premier League table.
7. Theo Walcott has scored four goals in his last four Premier League games v Manchester City, but he hasn’t scored in the league since December (against City).
8. These two sides have scored the most goals through substitutes in the Premier League this season – Arsenal (8) and Manchester City (7).
9. Guardiola has suffered five league defeats as Manchester City boss this season – he’s never lost six in a single league campaign as a manager.
10. Manchester City have won just four of their last 15 Premier League matches played on a Sunday (W4 D6 L5).
11. If all goals scored after the 85th minute in the Premier League this season were removed, Arsenal would be seven points worse off (more than any other side) and below West Brom and Everton in the table (8th).